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Filtered Search Results
Medchemexpress LLC 2-Hydroxyquinoline | 59-31-4 | 145.16 | 50 G
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2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase. With IC50 values of 64.4 μg/mL and 130.5 μg/mL respectively, it is utilized in the study of diabetes.
- Inhibits α-glucosidase (IC50: 64.4 μg/mL)
- Inhibits α-amylase (IC50: 130.5 μg/mL)
- Used in diabetes research
- Off-white to light yellow solid
- Soluble in DMSO (100 mg/mL)
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
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Ambeed AMBEED
5000870602 8-BROMO-6-NITROQUINOLINE 1GR
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Medchemexpress LLC Isoquinolin-4-amine | 23687-25-4 | 144.17 | 1 G
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Isoquinolin-4-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients. The appearance is a solid, off-white to light brown in color. It is soluble in DMSO.
- Biochemical reagent for life science research
- Solid, off-white to light brown in appearance
- Soluble in DMSO
- For research use only
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 25 G
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2-Aminoquinoline, also known as 2-Quinolinamine, is a promising compound primarily recognized as a bioavailable nNOS inhibitor. Despite exhibiting low human nNOS inhibition and selectivity against human eNOS, along with significant binding to other CNS targets, it demonstrates antiviral activity against the vaccinia virus. This compound holds potential for research in antineurodegenerative agents.
- Acts as a bioavailable nNOS inhibitor
- Shows antiviral activity against the vaccinia virus
- Potential for research into antineurodegenerative agents
- Appears as a solid
- For research use only
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Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 100 MG
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5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active, non-competitive 20S proteasome inhibitor. It has the ability to inhibit NF-κB activity and induce the death of cancer cells, while exhibiting low cytotoxicity towards normal hematopoietic cells. This compound can be utilized for research related to cancer, particularly leukemia.
- Orally active.
- Functions as a non-competitive 20S proteasome inhibitor.
- Inhibits NF-κB activity.
- Induces cancer cell death.
- Shows low cytotoxicity towards normal hematopoietic cells.
- Can be used for cancer research, including leukemia.
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Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 25 G
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7-Methylisatin is a derivative of Isatin and functions as a molecular block. This product is provided as a solid with a light yellow to orange appearance.
- Derivative of Isatin
- Utilized as a molecular block
- Solid appearance
- Light yellow to orange color
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Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 50 MG
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MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM) and has antitumor activity.
- Potent MDM2-p53 protein-protein interaction (PPI) inhibitor
- High binding affinity against MDM2 (Kd=8.2 nM)
- Antitumor activity
- Available in solid and solution forms
- Soluble in DMSO (≥ 53 mg/mL)
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eMolecules 91301-03-0 | 2-Hydroxyquinoline-3-carbaldehyde | Combi-Blocks | MFCD02642162 | 173.171 | C10H7NO2 | 95.000 | Oc1nc2ccccc2cc1C=O | 1g | 517033380
2-Hydroxyquinoline-3-carbaldehyde | Combi-Blocks | 91301-03-0 | MFCD02642162 | 173.171 | C10H7NO2 | 95.000 | Oc1nc2ccccc2cc1C=O | 1g | 517033380
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Ambeed AMBEED
5000885473 4-HYDROXYQUINOLINE-3-CAR 5G
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eMolecules 3945-69-5 | 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride | Combi-Blocks | MFCD03613550 | 276.720 | C10H17ClN4O3 | 95.000 | [Cl-].COc1nc(OC)nc(n1)[N+]1(C)CCOCC1 | 500g | 267182019
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride | Combi-Blocks | 3945-69-5 | MFCD03613550 | 276.720 | C10H17ClN4O3 | 95.000 | [Cl-].COc1nc(OC)nc(n1)[N+]1(C)CCOCC1 | 500g | 267182019
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eMolecules 7,8-DIHYDROQUINOLINE-2,5(1H,6H)-DIONE | 15450-69-8 | MFCD00766821 | 5g
AstaTech | 7,8-DIHYDROQUINOLINE-2,5(1H,6H)-DIONE | 5g | 443836014 | 81092 | 95.000 | 15450-69-8 | MFCD00766821 | 163.176 | C9H9NO2
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Medchemexpress LLC Q-VD-OPh | 1135695-98-5 | MFCD08669741 | 99.9% | 513.49 g/mol | C26H25F2N3O6 | 10MM 1ML
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Q-VD-OPh is an irreversible pan-caspase inhibitor used in research to block apoptosis. It inhibits caspase-7 with an IC50 of approximately 48 nM and shows inhibitory activity against multiple caspases (IC50 25-400 nM). The compound is cell-permeable, reported to cross the blood-brain barrier, and is provided as powder and as DMSO stock solutions for convenient preparation of working concentrations.
- Irreversible pan-caspase inhibitor with low-nanomolar potency against caspase-7.
- Activity against multiple caspases (IC50 range 25-400 nM).
- Cell-permeable and reported to cross the blood-brain barrier.
- Available as powder or pre-prepared DMSO stock for flexible use.
- High purity suitable for research applications (reported 99.9%).
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Medchemexpress LLC Mefloquine | 53230-10-7 | 100.0% | 378.31 | 5 MG
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Mefloquine is an orally active and potent quinoline antimalarial agent, also functioning as an anti-SARS-CoV-2 entry inhibitor and a K+ channel (KvQT1/minK) antagonist. It is suitable for various research applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM.
- Suitable for malaria research.
- Suitable for systemic lupus erythematosus research.
- Suitable for cancer research.
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5000885148 N2-DIMETHOXY-N-METHYLACE 10G
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Medchemexpress LLC Tigecycline | 220620-09-7 | 99.95% | 200 MG
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Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. It has been shown to inhibit AML2 and HL-60 cells, with specific IC50 values. Its activity extends to bacterial strains, demonstrating a mean inhibitory concentration (MIC) of approximately 125 ng/mL for E. coli (MG1655 strain), and MIC50 and MIC90 values of 1 and 2 mg/L, respectively, for Acinetobacter baumannii.
- Broad-spectrum glycylcycline antibiotic
- Inhibits AML2 and HL-60 cells in vitro
- Demonstrates activity against E. coli and Acinetobacter baumannii
- Light yellow to orange solid appearance
- Derived from microorganisms
- Reduced tumor volume and weight in an AML xenograft model
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